Case Study
Epilepsy Models and Preclinical Common Data Elements
References: Gorter J, van Vliet E, Dedeurwaerdere S, Buchannan G, Friedman D, Borges K, Grabenstatter H, Lukasiuk K, Scharfman H, Nehlig A (2018). “A companion to the preclinical common data elements for physiologic data in rodent epilepsy models. A report of the TASK3 Physiology Working Group of the ILAE/AES Joint Translational Task Force”.Epilepsia Open, 3(s1):69-89. Introduction Preclinical invivo epilepsy studies continue to evolve by maximizing the number of endpoints and biomarkers to better characterize the model being studied. This concept supports a multi-faceted approach recognizing organ systems work together and influence one another; suggesting specific pathologies cannot be described by simply studying one aspect. A joint translational task force reports