Email remains central to HCP engagement, with open rates climbing to 15.48% in 2023, up from 13.02% in 2022. Success hinges on personalization, integration of broadcast and triggered emails, storytelling, and segmentation. Gmail and Yahoo now require DMARC authentication and one-click unsubscribe, raising compliance standards. Benchmarks show oncology and respiratory segments improving through better targeting, with dermatology achieving the highest open rates. AI and GenAI are enhancing personalization, timing, and even content creation. Despite privacy and regulatory shifts, email continues to build trust, drive engagement, and anchor omnichannel HCP marketing.

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