CASE STUDY | CELL DISRUPTION Yeast Cell Disruption by Scalable High-Intensity Ultrasound (646) 580-4676 contact@sonomechanics.com Cell disruption (lysis) is necessary for many industries, including pharmaceutical, cosmetic, biotechnology, energy, nutraceutical, food & beverage and chemical. It is, for example, an important step in recombinant protein production for medical applications. Allied Innovative Systems (ALLIS) partnered with Industrial Sonomechanics (ISM) in order to determine the effectiveness of high-amplitude ultrasonic cell disruption and the feasibility of applying it on a large scale using Barbell Horn® Ultrasonic Technology (BHUT). ALLIS wanted to engage in a research and development project related to cell disruption of yeast cells. Since this is a very

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