After decades of effort, the long-sought goal of nationwide interoperability is within reach, raising the prospect of a new era in healthcare marked by seamless connectivity between patients, providers, payers, and other stakeholders. Driving today’s paradigm shift is the convergence of policy objectives and technical capabilities, coupled with a hard-won consensus about appropriate data-sharing standards. Major barriers remain, however, including patient matching and identity, data mapping, and appropriate security. Perhaps most importantly, embracing a more collaborative mindset will be essential for stakeholders who are long accustomed to exerting proprietary control over patient data for competitive advantage. Yet as the new ecosystem evolves, a more efficient and responsive

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