The new england journal of medicine n engl j med 379;21 nejm.org November 22, 2018 2015 The authors’ affiliations are listed in the Appendix. Address reprint requests to Dr. Freedman at the Sections of Emergency Medicine and Gastroenterology, Depart- ment of Pediatrics, Alberta Children’s Hos- pital and Research Institute, University of Calgary, 2888 Shaganappi Trail NW, Cal- gary, AB T3B 6A8, Canada, or at stephen . f r e e d m a n @ al b e r t ah e al t h s e r v i c e s . c a . * A complete list of the members of the PERC PROGUT Trial Group is provided in the Supplementary Appendix, avail- able at NEJM.org. N Engl J Med 2018;379:2015-26. DOI: 10.1056/NEJMoa1802597 Copyright © 2018 Massachusetts Medical Society. BACKGROUND Gastroenteritis accounts for approximately 1.7 million vis

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