The new england journal of medicine n engl j med 379;21 nejm.org November 22, 2018 2002 The authors’ affiliations are listed in the Appendix. Address reprint requests to Dr. Schnadower at the Department of Emer- gency Medicine, Cincinnati Children’s Hospital Medical Center, 3333 Burnet Ave., MLC 2008, Cincinnati, OH 45229, o r a t d a vi d . s c h n a d ow e r @ c c h m c . o r g . This article was updated on February 14, 2019, at NEJM.org. N Engl J Med 2018;379:2002-14. DOI: 10.1056/NEJMoa1802598 Copyright © 2018 Massachusetts Medical Society. BACKGROUND Acute gastroenteritis develops in millions of children in the United States every year, and treatment with probiotics is common. However, data to support the use of probiot- ics in this population are limited. METHODS We conducte

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