Mechanisms of Anti-Tumor Activity of STAT3 Degraders in Lymphoma Case Study
Mechanisms of Anti-Tumor Activity of STAT3 Degraders in Lymphoma Case Study
9 PagesHyperactivation of STAT3 promotes tumor cell-intrinsic gene expression programs involved with survival, proliferation, stemness and metastasis of tumor cells. Additionally, STAT3 promotes the differentiation and activity of immunosuppressive cells in the tumor microenvironment.
