STUDY PROTOCOL Open Access Multi-dose Oral Ondansetron for Pediatric Gastroenteritis: study Protocol for the multi-DOSE oral ondansetron for pediatric Acute GastroEnteritis (DOSE-AGE) pragmatic randomized controlled trial Stephen B. Freedman 1* , Sarah Williamson-Urquhart 2 , Anna Heath 3,4 , Petros Pechlivanoglou 5 , Gareth Hopkin 6 , Serge Gouin 7 , Amy C. Plint 8 , Andrew Dixon 9 , Darcy Beer 10 , Gary Joubert 11 , Christopher McCabe 12 , Yaron Finkelstein 13 , Terry P. Klassen 10 and on behalf of the KidsCAN-Pediatric Emergency Research Canada (PERC) Innovative Pediatric Clinical Trials DOSE-AGE Study Group Abstract Background: There are limited treatment options that clinicians can provide to children presenting to emergency departments with vomiting secondary to acute gastroenteritis

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