Fluidization Segregation During Pneumatic Transport to Bin The Need A contract pharmaceutical manufacturer was experiencing segregation of a fine powder blend during routine handling. A dense-phase pneumatic conveying system was used to transport the final blended material to a surge bin located above an encapsulation machine. The blend consisted of fine, active-rich, particles and several excipients with a substantially larger particle size. Though the blend did not experience segregation during pneumatic conveying, since the material was aerated during transport, the air trapped in the blend caused fluidization segregation to result during surge bin filling. This segregation yielded a concentration of fine particles (super potent) at the top surface of the blend after conveyance to t

Join for free to read