IQVIA’s PIERS team enhanced real-world data collection for a nonprofit registry project by upgrading its interoperability platform. Challenges included inconsistent site readiness, limited scalability for large patient volumes, and data quality issues. The solution applied HL7 FHIR with multimodal ingestion adapters, configurable validation, and automated harmonization. This cut data processing from weeks to hours, eased partner burden, and improved accuracy. Beyond this registry, the model offers a scalable, low-burden framework for high-volume EHR integration, enabling faster, higher-quality insights.

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