Paper 230-25 Automating the Selection of Controls in Case-Control Studies Edgar L. Mounib Thiru Satchi Blue Cross and Blue Shield of Massachusetts, Boston, Massachusetts Abstract A case-control study is an observational study in which subjects are classified according to the presence (‘cases’) or absence (‘controls’) of the outcome of interest. These controls can then be matched with cases according to a characteristic(s), to ensure the two groups are comparable for further analysis. However, this matching process can be difficult, time consuming, and costly. Hence, we developed a SAS ® program to automate the selection of controls, taking into account age, gender, and other user-defined criteria. This program can be adjusted to account for varying case-control ratios, thus affecting th

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