Computational Changes in the Analysis of Data from Case-Control Studies Olaf Gefeller, Annette Pfahlberg Department of Medical Statistics, University of Göttingen, F.R.G Abstract. Epidemiologic investigations devoted to the analysis of the etiology of diseases employ a variety of designs among which the case-control study is nowadays a popular representative. Important methodologic changes in design and analysis of a case-control study have taken place during the last decades. In addition, the market providing specialized and general purpose statistical software for the analysis of case-control data has also grown dramatically. In a standardized literature search in three leading epidemiologic journals based on nine yearly volumes within the time period 1955 - 1994 we analysed sy

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