This paper focuses on the challenge of accurately measuring the real-world impact of pharmaceutical interventions beyond traditional commercial metrics. It explores gaps between clinical evidence, patient outcomes, and payer expectations, emphasizing the need for integrated measurement frameworks. The report discusses the importance of real-world data, outcomes-based metrics, and cross-functional collaboration to demonstrate value across stakeholders. By aligning medical, commercial, and access strategies, organizations can better quantify impact on population health, healthcare efficiency, and system sustainability. The paper positions impact measurement as a strategic capability critical to trust, reimbursement, and long-term innovation.

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