This guide outlines six best practices for healthcare interoperability: adopt modern AI data platforms for secure, scalable data sharing; address financial and political considerations to align stakeholders; create a data-driven culture to improve outcomes; establish a center of excellence to unify analytics and foster collaboration; appoint a chief data officer to drive governance and strategy; and evaluate interoperability efforts regularly. Interoperability improves patient care, enables AI, reduces costs, and supports precision medicine but requires overcoming challenges like legacy systems, security concerns, and regulatory compliance.

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