Establishing DevOps security at scale requires six principles. First, instantiate security policy as code to eliminate manual errors and embed controls into infrastructure as code. Second, enforce separation of duties so developers, operators, and security each focus on their strengths. Third, maintain flow and velocity by integrating security early, using microservices, and applying Kanban to detect bottlenecks. Fourth, treat security as a first-class citizen with least privilege, secure vaults, vulnerability scans, and training. Fifth, automate security tasks like secret rotation and breach response to reduce human latency. Sixth, embrace new technologies, from serverless to identity-based models, to align with Zero Trust.

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