Application Note: AN 121B Global Headquarters: 32 Nixon RD, Unit 1, Bolton ON, L7E 1W2, Canada. Email: info@ionics.ca, Phone: 1-905-857-5665, Fax: 1-905-857-3040, www.ionics.ca For Research Use Only Ultra-Sensitive Direct Quantitation of Thyroid Hormones in Serum by LC-MS/MS 1. Introduction Thyroid hormones, 3,3',5 Triiodothyronine and Thyroxine (T3 and T4 respectively) are endogenous hormones derived from tyrosine with iodi

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