PK/PD RELATIONSHIP IN TARGETED PROTEIN DEGRADATION (TPD)
PK/PD RELATIONSHIP IN TARGETED PROTEIN DEGRADATION (TPD)
19 PagesThe delay in PK/PD relationship of TPD largely stems from its mechanism of action. Study the temporal PK/PD relationship in vivo is key to understand the interplay between drug-and system-parameters. Mechanism PK/PD modeling is a useful tool to dissect the PK/PD interplay in vivo and to facilitate human dose projection.
