Case Study
How The Mixer Torque Rheometer Resolved A Tablet Friability Issue
AN APPLICATION NOTE HOW THE MIXER TORQUE RHEOMETER RESOLVED A TABLET FRIABILITY ISSUE AN APPLICATION NOTE CALEVA The hand squeeze test. Is this the right way?2 BACKGROUND Company “A” produce a range of tablets as food supplements from natural materials, plant extracts and other natural food sources. Most tablet formulations work well and company “A” has a good reputation for their products. Generally they do not encounter problems with the tablets breaking or disintigrating during manufacture, packing or storage. However, one product using a particular plant extract tablet was constantly giving problems. The manufacturing process consisted, in part, of manual hand mixing by a group of four operators of all the formulation ingredients in a large pot. The mixing was continued until