From 34-mer peptide to small molecule: Using fields to find new actives for a GPCR receptor from the natural peptide ligand
From 34-mer peptide to small molecule: Using fields to find new actives for a GPCR receptor from the natural peptide ligand
2 PagesFrom 34-mer peptide to small molecule: Using fields to find new actives for a GPCR receptor from the natural peptide ligand J. A. Vinter † † Cresset, New Cambridge House, Bassingbourn Road, Litlington, Cambridgeshire, SG8 0SS, UK Abstract Cresset consultants were asked to identify novel active compounds for a class-II GPCR receptor. There were no known small molecule inhibitors, so the only information available was the natural ligand, a
