Case Study

Development and implementation of hybrid LBA-LC-MS/MS assays for quantitation of biotherapeutics in plasma.

Development and implementation of hybrid LBA-LC-MS/MS assays for quantitation of biotherapeutics in plasma.

Pages 1 Pages

For Research Use Only. Not for use in diagnostic procedures. AB Sciex is operating as SCIEX. © 2017 AB Sciex. The trademarks mentioned herein are the property of the AB Sciex Pte. Ltd. or their respective owners. AB SciexTM is being used under license. RUO-MKT-20-6470-A Case Study The Challenges • Training a diverse team of scientists in protein quantification • Developing a selective and highly sensitive MS/MS assay for a biotherapeutic target in plasma • Choosing the best signature peptides for quantitation • Optimization of sample enrichment and chromatographic conditions The Solution SCIEX Biologics Quant Platform • Immunoaffinity enrichment sample prep kit with lab tested protocols • High sensitivity LC - MS/MS hardware • Powerful software for peptide MRM optimizatio

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