Case Study

Can We Use Homology Models in Protein-protein Docking?

Can We Use Homology Models in Protein-protein Docking?

CAN WE USE HOMOLOGY MODELS IN PROTEIN-PROTEIN DOCKING? Christoph Schneider, christoph@accelrys.com Accelrys, Inselkammerstr.1, 82008 Unterhaching, Germany Introduction Structures of macromolecular complexes are necessary for a mechanistic description and understanding of biochemical and cellular processes. The formation of a protein- protein complex normally has a functional consequence (e.g. signal transduction), but may also be responsible fo

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