This white paper describes the shift toward a self-orchestrating, autonomous supply chain driven by digitization, real-time data, AI, and a unified cloud network. Page 1 explains that autonomy means integrated planning, ordering, production, and delivery powered by predictive and prescriptive analytics. Pages 2–4 highlight the human–machine partnership, the need to eliminate silos, and the importance of digitizing documents, workflows, and partner connections. Pages 5–7 show how machine learning evolves from predicting to prescribing actions, improving ETAs, pricing, and inventory decisions. Page 8 outlines key questions and recommendations for building an autonomous roadmap focused on data quality, network connectivity, and continuous learning across the supply chain.

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