This Trinity white paper addresses how siloed working across life sciences organizations undermines strategy, delays decisions, and weakens patient outcomes. It identifies four critical areas where silos emerge: strategic planning, value proposition development, evidence generation, and patient support programs. Common pitfalls include misaligned strategies, fragmented value messaging, and disconnected patient initiatives. The paper calls for integrated, cross-functional collaboration supported by clear leadership, governance, and external facilitation. Leaders must reinforce synergy, encourage healthy challenge, and unify teams under a shared purpose to translate scientific innovation into improved patient and business outcomes.

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