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CXCL13 is a predictive biomarker in idiopathic multicentric Castleman disease

CXCL13 is a predictive biomarker in idiopathic multicentric Castleman disease

Pages 13 Pages

Idiopathic multicentric Castleman disease (iMCD) is a rare and poorly understood cytokine storm driven inflammatory disorder.Interleukin-6(IL-6) is a known disease driver in some patients, but anti-IL-6 therapy with siltux-imabis not effective in all patients, and biomarkers indicating success at an early time point following treatment initiation are lacking.

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