Clinical trial participant payments are critical for recruitment and retention, yet managing them globally is complex. Nearly 90% of patients cite compensation as a motivator, but only 28% trust payments will be delivered as promised. Traditional site-managed systems burden staff, delay reimbursements, and risk regulatory noncompliance. Country-level challenges compound the issue: China’s strict approvals, anti-bribery, and data privacy laws; Brazil’s dual ethics approvals and post-trial access mandates; Bulgaria’s GDPR and banking scrutiny. IQVIA highlights the need for global, technology-driven platforms with local expertise to streamline payments, reduce burden, and enhance trial success.

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