This integration brief outlines how Proofpoint and Microsoft Defender provide multilayered defense against email-borne threats. Proofpoint TAP detects malicious files and URLs, while Microsoft Defender tracks endpoint activity, enabling complete visibility into user and device risks. Benefits include reduced remediation times, SOC efficiency, and improved threat protection. Proofpoint TRAP further automates removal of malicious messages. Together, the solutions close detection gaps, enhance visibility, and mitigate both phishing and BEC threats across cloud and hybrid environments.

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