Organizations operating in the U.S. must screen individuals, companies, and transactions against sanctions and politically exposed person (PEP) lists to prevent illicit activities. Certain businesses face heightened regulatory scrutiny. Key risk factors include international operations, involvement in import/export activities, emerging industries like cannabis, cryptocurrency exchanges, and insufficient compliance controls. Examples of violations in 2021 include significant fines for companies such as Union de Banques Arabes et Françaises, Cameron International, and BitPay for breaching sanctions. Organizations must have effective screening programs to avoid penalties.

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