Case Study

Virtual Screening with 11ßHSD-1 Resulting in Diverse New Leads

Virtual Screening with 11ßHSD-1 Resulting in Diverse New Leads

Pages 2 Pages

Virtual Screening with 11 ßHSD-1 Resulting in Diverse New Leads J. G. Vinter † , T. Cheeseright † † Cresset, New Cambridge House, Bassingbourn Road, Litlington, Cambridgeshire, SG8 0SS, UK Abstract The enzyme 11ßHSD-1 is highly expressed in key metabolic tissues and has been linked with the control of visceral fat deposition. Our client asked Cresset’s consulting team to generate new ideas for lead structures in this area, using the natur

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