ORIGINAL RESEARCH Use of a Long-Acting Opioid Microsphere Formulation to Overcome Difficulties in Swallowing Pain Medication This article was published in the following Dove Press journal: Journal of Pain Research Nathan Anderson 1 Andrea G Gillman 1 Ajay D Wasan 1,2 1 Department of Anesthesiology and Perioperative Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; 2 UPMC Pain Medicine, Pittsburgh, PA, USA Purpose: XtampzaER ® (XER)isalong-actingoxycodoneformulationwhichwasdesignedto be abuse-deterrent and to overcome capsule-swallowing issues. This pilot study evaluated the effectivenessofXERatreducingswallowingdifficultywhileprovidingeffectiveanalgesiainthe settingofchronicpain. Subjects and Methods: Eleven subjects with chronic pain who reported pill-swallowing

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