Case Study

TwinStrand Biosciences: Overcoming Bioinformatics Challenges to Rapidly Scale Genomics Pipelines

TwinStrand Biosciences: Overcoming Bioinformatics Challenges to Rapidly Scale Genomics Pipelines

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COMPANY OVERVIEW Dedicated to Detecting Ultra-Rare Variants with Unparalleled Sensitivity and Specificity TwinStrand Biosciences is a Seattle-based genomics company developing methods for detecting ultra-low frequency genetic variants that are not possible to detect by conventional methods. TwinStrand Duplex SequencingTM technology uses proprietary biochemistry and bioinformatics to improve the accuracy of next-generation sequencing (NGS) by over 10,000-fold. DuplexSeq TM technology is used by researchers across the genomics landscape, including those who are studying mutational signatures, measureable residual disease (MRD), cellular immunotherapy persistence, and other applications that require the detection of low-frequency variants. Essentially, it supports anyone lookin

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