Supporting organisations in gaining value from process understanding The Use of BRITEST in Drug Product Development + Increase in parameter causes a positive effect on the process - Increase in parameter causes a negative effect on the process Unmic Particle Enters Microniser Particle Enters Jet Particle Acceleration Particle-Particle Collision Particle-Wall Collision Particle Breakage Particle Enters Cyclone Particle Enters Collection Vessel Particles Deposit on Side of Microniser Unmic Particle Enters Cyclone Particle Acquires Charge Particle Becomes Amorphous Reverse Flow Particle Exits Cyclone & Enters Filter Particles Deposit on Top of Microniser Particles Deposit on Bottom of Micronise

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