Smarter chemical synthesis – with Novozymes enzymes for biocatalysis Introduction Biocatalysis is the application of enzymes to replace chemical catalysts in synthetic processes. In recent past, the use of biocatalysis has gained momentum in the chemical and pharmaceutical industries. Today, it’s an important tool for medicinal, process and polymer chemists to develop efficient and highly attractive organic synthetic processes on an industrial scale. The biocatalytic process for Pregabalin has been developed by Pfizer to boost efficiency in Pregabalin production using Novozymes Lipolase ® . Development of the biocatalytic process for Pregabalin involves four stages: • Screening to identify a suitable enzyme • Performing optimization of the enzymatic reaction to optimize through

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