Supporting organisations in gaining value from process understanding Con t a c t +44(0)1925 607030 enquiries@britest.co.uk www.britest.co.uk Challenge A ‘simple’ plant cleaning process to enable changeover between chemical steps in inkjet dye synthesis currently required 2-3 days for three reactor vessels equipped with Clean-In-Place (CIP) equipment, including spray balls and jetters. A reduction in cleaning timelines was required due to capacity constraints. Approach A Britest methodology developed in collaboration with the Irish Pharmaceutical Manufacturing Technology Centre (PMTC) to support the optimisation of changeover/cleaning processes was applied in a one-day workshop. This involved technical, process engineering, continuous improvement and manufacturing function

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