Mya 4 is providing reliable results to Johnson Matthey The Situation The chemists in the Development department at Johnson Matthey Edinburgh are undertaking numerous projects to study key processing parameters during manufacture of active pharmaceutical ingredients. Experimental studies of one process in particular required highly accurate temperature control. The Development department chemists were using a parallel reactor vessel with a ?uid-?lled heat / cool package for experimental studies. The parallel reactor vessel consisted of six reactor vessels housed in an aluminium jacket. It transpired that the temperature pro?le was not uniform in each of the reaction vessels. The lack of uniformity in temperature pro?les between equivalent experiments was causing subtle, but statistically me

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