Large-Scale GMP Manufacturing with Customized Bioreactor for Photoautotrophic Organisms Promising pilot-scale project with the world’s first 500L single-use bioreactor that can be adapted for any manufacturing process requiring light as an energy source. Sartorius fitted the BIOSTAT ® STR 500 single-use bioreactor with more than 5000 LEDs for Greenovation’s commercial moss production facility in Germany Success Story BryoTechnology, a biopharmaceutical manufacturing technology based on moss-plants, is one of the next generation manufacturing technologies for biopharmaceuticals 1 . The process developed by Greenovation (Heilbronn, Germany), uses the genetically modified moss Physcomitrella patens to produce complex human enzymes to treat rare diseases (orphan drugs) 2 .

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