Case Study

Independent, Centralized Image Review and Analyses Supporting Development of VK2809 to Treat NAFLD/NASH

Independent, Centralized Image Review and Analyses Supporting Development of VK2809 to Treat NAFLD/NASH

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Independent, Centralized Image Review and Analyses Supporting Development of VK2809 to Treat NAFLD/NASH Introduction Non-alcoholic fatty liver disease (NAFLD) and its progression to non-alcoholic steatohepatitis (NASH), is estimated to become the most common chronic liver condition in Western populations. This increased prevalence is related to the increase in lifestyle-related diseases – due to the shared risk factors of obesity, insulin sensitivity, and poor diet and exercise habits. However, the etiology of NAFLD/NASH is not well understood – the diseases’ multifactorial nature is a contributing factor and challenges drug development. Although sponsors are racing through Phase III trials, there has been limited success, and no drug is currently approved for treatment. Th

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