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How Efficient is Your Lab? Part IV - Maintaining Optimal Sample Quality During Transportation

How Efficient is Your Lab? Part IV - Maintaining Optimal Sample Quality During Transportation

Consumables & Instruments azenta.com How Efficient is Your Lab? Part IV - Maintaining Optimal Sample Quality During Transportation WHITE PAPERAzenta Life Sciences 2 Consumables & Instruments | White Paper Introduction Cryogenic samples such as eukaryotic cell-based therapeutics require storage at temperatures below the threshold for the glass transition phase of water (Tg-H2O, approximately -135°C). Storage under those conditions avoids biological activity and minimizes loss of post-thaw cell viability 1 . Keeping eukaryotic cell solutions at temperatures higher than Tg-H2O introduces serious risks. When encapsulated liver cell spheroids were stored at -80°C, decreased viable cell numbers and cell function were detected after just one month of storage compared with the same cel

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