Binary solvent mixtures are used as car- riers in production scale pharmaceutical HPLC separations. Analysis of the mix- ture ratios is required prior to injection into the HPLC column. The correct mix- ture ratio ensures ef? cient and correct separation of the chemical targeted for separation. Concentrations of individual solvents can be measured over the en- tire range from 0 to 100%. Traditionally these analyses are made using labora- t

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