Expert advice on DXA in clinical trials Challenge Dual-energy X-ray absorptiometry (DXA) has been used extensively in clinical trials in osteoporosis. DXA is increasingly being used to examine bone density in trials of drugs that could have unwanted effects on bone, and for studies evaluating adipose tissue and muscle – for example studies of obesity, sarcopenia or cachexia. DXA is one of the few truly quantitative imaging techniques, as a numerical output is obtained in the scan and not derived later from the image; it counts the number of photons that are lost as they pass through patients, and bone, fat and muscle absorb X rays differentially. Several clients have sought our support to understand DXA, including DXA platform developers, companies running clinical trials that include DXA

Join for free to read