Case Study
BacteremiaAntibioticLengthActuallyNeededfor ClinicalEffectiveness(BALANCE):studyprotocol forapilotrandomizedcontrolledtrial
BacteremiaAntibioticLengthActuallyNeededfor ClinicalEffectiveness(BALANCE):studyprotocol forapilotrandomizedcontrolledtrial
STUDY PROTOCOL Open Access Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE): study protocol for a pilot randomized controlled trial Nick Daneman 1* , Asgar H Rishu 2 , Wei Xiong 2 , Sean M Bagshaw 3 , Deborah J Cook 4 , Peter Dodek 5 , Richard Hall 6 , Anand Kumar 7 , Francois Lamontagne 8 , Francois Lauzier 9 , John C Marshall 10 , Claudio M Martin 11 , Lauralyn McIntyre 12 , John Muscedere 13 , Steven Reynolds 14 , Henry T Stelfox 15 , Robert A Fowler 16 and on behalf of the Canadian Critical Care Trials Group Abstract Background: Bacteremia is a leading cause of mortality and morbidity in critically ill adults. No previous randomized controlled trials have directly compared shorter versus longer durations of antimicrobial treatment in these patients. Met